Active Pharmaceutical Ingredient (API) Experience
Pfizer | Bulk Manufacturing Facility | Tuas, Singapore
At Jacobs, we are experienced with the current trends and technology in Active Pharmaceutical Ingredient (API) manufacturing – but that is not enough. We apply our expertise in determining which design and technology truly adds value in safety and quality; what reduces cost and improves schedule. We provide solutions to your challenges. We design and build facilities from lab scale to pilot plant to commercial manufacturing scale – with sizes ranging from single clinical suite to some of the largest plants in the world. Whether they are API for novel products for start-up companies to high volume plants for mature global pharmaceutical companies – we deliver solutions.
We work with clients in developing commercialization techniques for large and small scale API applying advanced analytics, P.A.T., and continuous manufacturing technologies. We consider the key criteria for an integrated process and facility design that minimizes product turnovers while providing effective use of state of the art containment technology. Our Subject Matter Experts are leaders in API design and innovative technology. We understand that the current small molecule API processing is changing to provide faster supply to market, easily handle progressive more potent materials with a higher requirement for GMP and increase system cleaning efficiency. We are on the forefront with our clients in the development of new kilo lab, clinical scale and production facilities that address these issues.
Types of Manufacturing and Support Areas designed include:
- Dispensary
- Glass-lined Reactors
- Isolation
- Drying
- Solvent Tank Farm / Recovery
- Warehousing
- Process Utilities Infrastructure
- Clean Utilities
- Environmental Treatment
Boehringer Ingelheim | API Synthesis II Project | Fornovo San Giovanni, Italy
Janssen | Chemical Development Pilot Plant | Geel, Belgium
Manufacturing Technology includes:
- Multi-purpose
- High Containment
- Cryogenic / High Energy
- Filter Dryer / Agitated Dryer
- Waste Treatment Minimization
- Milling / Blending
- CIP
- Modular
- Membrane Separation

Jacobs leads the global professional services sector providing solutions for a more connected, sustainable world. jacobs.com